Tamoxifen blocks the actions of estrogen and is used to treat and prevent some types of breast cancer -onlinepillmart

What is Tamoxifen ?

Tamoxifen is a type of medicine known as an ‘anti-oestrogen’. It is mainly used to treat women with breast cancers that respond to the female sex hormone, oestrogen.

Mechanism of action:

Most breast cancers are sensitive to oestrogen, and their growth is increased in the presence of this hormone. Oestrogen binds to oestrogen receptors on the breast cancer cells and causes changes within the cells that result in faster growth of the cancer. Breast cancers that are sensitive to oestrogen are called oestrogen receptor positive cancers.
Tamoxifen works by blocking the oestrogen receptors, thereby blocking the effect of oestrogen on the cancer. This starves the breast cancer cells and stops them from growing.
This drug helps to prevent breast cancer from spreading to other areas of the body and also reduces risk of developing cancer in the other breast.

Warning:

This tablets may cause visual disturbances and lightheadedness and so could affect your ability to drive safely. You should make sure you know how this medicine affects you before driving or operating machinary.As this medicine may potentially cause harm to a developing baby, it should not be used during pregnancy. Women who have not yet passed the menopause should use a non-hormonal method of contraception to prevent pregnancy both during, and for two months following, treatment with this medicine.This drug is associated with a small increase in the risk of endometrial cancer. The benefits of taking tamoxifen to treat breast cancer outweigh this risk. However, to minimise the risk you should tell your doctor straight away if you experience any abnormal gynaecological symptoms during or after treatment with this medicine, so that they can be investigated. Symptoms to report include vaginal bleeding, menstrual irregularities,vaginal discharge, or symptoms such as pelvic pain or pressure. Ask your doctor for further information if you are concerned about this.It is associated with an increased risk of abnormal blood clots in the blood vessels (for example deep vein thrombosis or pulmonary embolism), particularly during periods of immobilisation and following surgery. The benefits of taking tamoxifen to treat breast cancer outweigh this risk. However, you should consult your doctor immediately if you experience any of the following symptoms during treatment, as they could be signs of a blood clot: stabbing pains and/or unusual swelling in one leg, pain on breathing or coughing, sudden breathlessness or sudden severe chest pain. Ask your doctor for further information if you are concerned about this.

Storage:

Store at room temperature. Protect from heat, light and moisture. Keep away from reach of children.

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